Subject baseline characteristics

Subject baseline characteristics

Getting Started
As a prescriber, you will be bombarded with information about new medications and may even feel pressure to prescribe them. This information and pressure may come from drug reps, journal advertisements, and even patients. The journal club/article review is meant to help you learn to make your own judgments regarding the importance of a new medication (or new indication).

Upon successful completion of the course material, you will be able to:

Take a primary research study and make an informed decision regarding the significance of the study.
Apply study results to practice.

Resources
Textbook: Pharmacotherapeutics for Advanced Practice Providers
Lexi-Comp (available via Up-to-Date) or other suitable drug/disease reference.
Suggested treatment guidelines/recommendations for this workshop
Chosen article and any other necessary references

Instructions
Review the rubric to make sure you understand the criteria for earning your grade.
Chose an article of interest to you from one of your professional journals and critique it. As indicated in the syllabus, the desired article is one of the primary research. It should involve statistical analysis of a pharmaceutical agent that is being compared to another medication or a placebo. The article can pertain to a new medication, or a new indication for an existing medication but it must be studied in subjects requiring treatment, not healthy volunteers.
Include at least the following in your analysis of the article (see example here):
Title of the article (including journal reference)
Study objective(s)
Study design
Overall design
Study endpoints (primary, secondary, etc.)
Inclusion/exclusion criteria
Subject baseline characteristics
Results
Efficacy and safety outcomes, if applicable
Statistical significance (p-values, confidence intervals, etc. as applicable)
Personal conclusions
Personal thoughts on the study
Impact to practice
How might the study change the way we practice?
The article review should be written using APA style.
When you have completed your assignment, save a copy for yourself and submit a copy to your faculty by day seven of the workshop (Turnitin enabled).

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